| Bullet train |
| LeSean McCoy | Philadelphia Eagles | Best of the bunch for 2012 |
| Arian Foster | Houston Texans | Excels as both a runner and a receiver |
| Ray Rice | Baltimore Ravens | Ready to show he was worth a new contract |
| Maurice Jones-Drew | Jacksonville Jaguars | The defending rushing champ has to shoulder a huge load in Jacksonville |
| Riding the Acela |
| Chris Johnson | Tennessee Titans | Needs to show last year was simply a fluke |
| Ryan Mathews | San Diego Chargers | Everyone expects great things this year, will he deliver? |
| Matt Forte | Chicago Bears | With a new contract in hand, expect big things from the Bears back |
| Darren McFadden | Oakland Raiders | Can he stay healthy enough to be a marquee back this year? |
| DeMarco Murray | Dallas Cowboys | Will be the focal point of a good offense |
| Jamaal Charles | Kansas City Chiefs | A top 5 pick prior to last year's injury, Charles is a year away from being totally back |
| Steven Jackson | St. Louis Rams | May be slowing down- but only a little bit |
| Marshawn Lynch | Seattle Seahawks | Would have been higher if not for off-field issues |
| Adrian Peterson | Minnesota Vikings | Have to keep a close eye on whether or not he will be placed on the PUP list |
| Highway driving |
| Fred Jackson | Buffalo Bills | Buffalo will rely less on Jackson and more on others in 2012 |
| Michael Turner | Atlanta Falcons | 2012 should be the year we see Turner lose effectiveness |
| Frank Gore | San Francisco 49ers | Look for less of a workload for Gore in 2012 |
| Reggie Bush | Miami Dolphins | Can Bush repeat his 2011 performance? |
| Ahmad Bradshaw | New York Giants | Look for the Giants to get David Wilson a lot of touches in 2012 |
| Trent Richardson | Cleveland Browns | Will get every opportunity to excel in 2012 |
| Roy Helu | Washington Redskins | Will RGIII take some goal line opportunities away from Helu? |
| Darren Sproles | New Orleans Saints | Pass-catching ability makes him the best guy to grab in a crowded backfield |
| Riding the Subway |
| Isaac Redman | Pittsburgh Steelers | Mendenhall's injury gives Redman a chance to shine |
| Pierre Thomas | New Orleans Saints | Needs to make the most of a limited number of touches |
| BenJarvus Green-Ellis | Cincinnati Bengals | Do not expect the change of scenery to effect Green-Ellis much |
| Shonn Greene | New York Jets | This may be his last chance to be the main back for the Jets if he does not produce |
| Mikel Leshoure | Detroit Lions | Even more valuable if Jahvid Best cannot suit up |
| Willis McGahee | Denver Broncos | Do not expect a repeat of 2011 for McGahee |
| Beanie Wells | Arizona Cardinals | Expect a fairly even split in carries with Ryan Williams |
| Ryan Williams | Arizona Cardinals | See above |
| Stevan Ridley | New England Patriots | You never know what to expect from backs running for Bill Belichick |
| DeAngelo Williams | Carolina Panthers | Too many quality running options in Carolina for Williams to put up huge numbers |
| Jonathan Stewart | Carolina Panthers | See above |
| James Starks | Green Bay Packers | After not living up to expectations in 2011, Starks has company in the Green Bay backfield |
| Kendall Hunter | San Francisco 49ers | Hunter is going to need to make the most of his opportunities |
| Kevin Smith | Detroit Lions | Even more valuable if he wins the starting spot during training camp |
| Taking the Bus |
| LeGarrette Blount | Tampa Bay Buccaneers | The arrival of Doug Martin means less action for Blount |
| Peyton Hillis | Kansas City Chiefs | He will get carries in KC, but not nearly as many as he saw in Cleveland |
| CJ Spiller | Buffalo Bills | Has the big play ability to have a big week or two |
| Ronnie Hillman | Denver Broncos | Denver will keep McGahee fresh by using Hillman a lot |
| David Wilson | New York Giants | It will be interesting to see how his role evolves throughout the year |
| Toby Gerhart | Minnesota Vikings | More valuable early in the year as Adrian Peterson works back from injury |
| Donald Brown | Indianapolis Colts | Will not get enough opportunity to be a stud back |
| Felix Jones | Dallas Cowboys | Will see role reduced in 2012 |
| Ben Tate | Houston Texans | Arian Foster is too good to allow Tate to be a major factor |
| Michael Bush | Chicago Bears | Will he get all the goal line carries for the Bears? |
| Jacquizz Rodgers | Atlanta Falcons | Will see more action in 2012 to keep Michael Turner fresh |
| Daniel Thomas | Miami Dolphins | Thomas needs to show something in 2012 to prevent Miami from looking for a replacement |
| Tim Hightower | Washington Redskins | Mike Shanahan still like Hightower a bunch |
| Alex Green | Green Bay Packers | Green has a chance to grab a prominent role for the Pack |
| Mark Ingram | New Orleans Saints | Needs a better sophomore season to stay relevant |
| Jahvid Best | Detroit Lions | Health is the reason Best remains a wild card |
| Walking home |
| Danny Woodhead | New England Patriots | More valuable in PPR leagues |
| Bernard Scott | Cincinnati Bengals | Solid guy to have on your bench |
| Robert Turbin | Seattle Seahawks | Will be used only to spell Marshawn Lynch |
| Evan Royster | Washington Redskins | Not a lot of touches left in the DC backfield |
| Mike Goodson | Oakland Raiders | A lot of guys are fighting for carries that do not go to Darren McFadden |
| Taiwan Jones | Oakland Raiders | See above |
| Delone Carter | Indianapolis Colts | If Donald Brown is not productive, Carter could see more work |
| Isaiah Pead | St. Louis Rams | Pead should get a few touches when Steven Jackson needs a breather |
| Lamar Miller | Miami Dolphins | If Bush falters, look for Miller to get a lot of touches |
| Shane Vereen | New England Patriots | Will probably have 1 or 2 stellar games throughout the year |
| Dion Lewis | Philadelphia Eagles | Versatile back should be good when he gets on the field |
| Rashad Jennings | Jacksonville Jaguars | Value shoots up if MJD continues to hold out |
| Bilal Powell | New York Jets | There will be opportunities to earn playing time in New York this year |
| Dexter McCluster | Kansas City Chiefs | Needs to establish a role before he loses his roster spot |